Southern African HIV Clinicians Society Paediatric Discussion Group

Southern African HIV Clinicians Society adult antiretroviral therapy guidelines: Update on when to initiate antiretroviral therapy

The most recent version of the Southern African HIV Clinicians Society's adult antiretroviral therapy (ART) guidelines was published in December 2014. In the 27 August 2015 edition of the New England Journal of Medicine, two seminal randomised controlled trials that addressed the optimal timing of ART in HIV-infected patients with high CD4 counts were published: Strategic timing of antiretrovir...

Canadian Paediatric Society

This statement is intended for health care professionals caring for neonates (preterm to 1 month of age). The objectives of this statement are to: 1. Increase awareness that neonates experience pain; 2. Provide a physiological basis for neonatal pain and stress assessment and management by health care professionals; 3. Make recommendations for reduced exposure of the neonate to noxious stimuli ...

Paediatric Pathology Society

showed increased AChE activity. 7 patients ultimately proved to be cases of Hirschsprung's disease; all but one of the rectal biopsies showed an increased AChE activity in the mucosa, and all biopsies showed an increased activity in the submucosa. From the investigation of resected bowel segments it was shown that the strongest activity occurred in the most distal part of the aganglionic bowel ...

Paediatric Research Society 671

Propionicacidaemia in twins. F. Cockburn, M. D. Cohen, J. A. B. Darling, M. Giles, R. A. Harkness, and A. D. Nicol. (Departments of Child Life and Health and Paediatric Biochemistry, University of Edinburgh, and Simpson Memorial Maternity Pavilion, Royal Infirmary, Edinburgh.) A few infants with a serious metabolic disease associated with increased concentrations of propionic acid in the plasma...

VON WILLEBRAND DISEASE A Discussion for Clinicians